Also known as: PlGF, pre-eclampsia marker, Human Placental Growth Factor
Specimen requirements
Sample type: Serum
Collection requirements: No special requirements
Cost
Price on application
Turnaround time
Analytical method
Immunoassay
Analysis undertaken at these site(s)
John Radcliffe Hospital
Reference intervals
sFlt and PlGF are analysed in the context of suspected pre-eclampsia in accordance with NICE guidance DG23.
Concentrations of both markers change throughout pregnancy, so interpretation is on the basis of the sFlt : PlGF ratio and local guidance is available on the hospital intranet [ouh.oxnet.nhs.uk/maternity] under Maternity Guidelines.
A ratio <38 between 20 and 34+6 weeks' gestation with a singleton pregnancy is associated with low risk (0.4 percent within seven days).
