Also known as: GBM; Goodpastures
Anti glomerular basement membrane antibodies are found in Goodpasture's syndrome and levels correlate with disease activity and often predict clinical outcome. The autoantibody is directed against the NC1 domain of the α- chain of type IV collagen. Approximately 25% of patients presenting with anti GBM antibodies also present with anti-neutrophil cytoplasmic antibodies, so parallel testing is recommended.
Specimen requirements
Serum 1ml
Cost
Price on application
Laboratory turnaround time
3 days
Laboratory method
CLiA - Automated Chemiluminescent Immunoassay
Reference range/units
2.9 - 18.9 CU = Negative
19.0 - 21.0 CU = Equivocal
> = 21.1 CU = Positive
Associated tests
Sample stability
2 months at 2-8ºC
Shipping and storage
UK and Ireland
Ambient temperature and first class post. Hays DX users please enquire via email below.
International
Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.
Ensure delivery Monday to Friday 09:00 - 17:30.
Further information and contact details
For further information, email immunologylab.enquiries@ouh.nhs.uk