Also known as: Mast Cell Tryptase; Serum Tryptase
Serum Tryptase is a marker of mast cell degranulation. Tryptase measurement is of value in the assessment of selected cases of anaphylactic/anaphylactoid reactions and in the investigation of suspected mastocytosis. An elevated tryptase does not distinguish between anaphylaxis and anaphylactoid reactions. Also see investigation of anaesthetic reactions.
In the investigation of anaphylaxis 3 blood samples should be taken recorded with the time and date of collection:
- At the time of the reaction (within 1 hour or as soon as possible)
- No later than 4 hours post onset of symptoms
- A future random sample to determine baseline level
Specimen requirements
Serum 1ml. Serum preferred but can test Plasma
Cost
Price on application
Laboratory turnaround time
3 days
Laboratory method
Immunocap automated Enzyme Immunoassay
Reference range/units
0-16 micrograms per litre
Associated tests
- Total IgE
- Specific IgE
Sample stability
2 months at 2-8ºC
Shipping and storage
UK and Ireland
Ambient temperature and first class post. Hays DX users please enquire via email below.
International
Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.
Ensure delivery Monday to Friday 09:00 - 17:30.
Further information and contact details
For further information, email immunologylab.enquiries@ouh.nhs.uk
